2faf Summary

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The structure of chicken mitochondrial PEPCK.

The structure was published by Holyoak, T., Sullivan, S.M., and Nowak, T., in 2006 in a paper entitled "Structural Insights into the Mechanism of PEPCK Catalysis" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Phosphoenolpyruvate carboxykinase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Phosphoenolpyruvate carboxykinase P21642 (34-128) (PCKGM_CHICK)search ,
P21642 (129-641) (PCKGM_CHICK)search
Gallus gallussearch ,
Gallus gallussearch
< 90% ,
< 90%
608 98%
B Phosphoenolpyruvate carboxykinase P21642 (34-128) (PCKGM_CHICK)search ,
P21642 (129-641) (PCKGM_CHICK)search
Gallus gallussearch ,
Gallus gallussearch
< 90% ,
< 90%
608 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P21642 (34 - 128) Phosphoenolpyruvate carboxykinase Gallus gallus

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Phosphoenolpyruvate Carboxykinase, domain 1search, Phosphoenolpyruvate Carboxykinase, domain 2search, Phosphoenolpyruvate Carboxykinase; domain 3search Phosphoenolpyruvate carboxykinasesearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (P21642) gluconeogenesissearch phosphoenolpyruvate carboxykinase activitysearch purine nucleotide bindingsearch GTP bindingsearch phosphoenolpyruvate carboxykinase (GTP) activitysearch

Chain InterPro annotation
A, B Phosphoenolpyruvate carboxykinase, GTP-utilisingsearch Phosphoenolpyruvate carboxykinase, N-terminalsearch Phosphoenolpyruvate carboxykinase, C-terminalsearch Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved sitesearch