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PDBe Entry: 2f7p 
Golgi alpha-mannosidase II complex with benzyl-mannostatin A
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 1.28 Å, R-factor: 16.7%, Free R-factor: 18.0%, Spacegroup: P 21 21 21
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04/07/2006, deposition: 01/12/2005, last revision: 24/02/2009
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Kuntz, D.A.; Rose, D.R.
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Structural Basis of the Inhibition of Golgi alpha-Mannosidase II by Mannostatin A and the Role of the Thiomethyl Moiety in Ligand-Protein Interactions.
J.AM.CHEM.SOC. vol:128, pag:8310-8319 (2006) [PubMed ID 16787095 ]
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GLYCOSYL HYDROLASE FAMILY 38
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3.2.1.114 ExPASy BRENDA (A)
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Drosophila melanogaster(fruit fly) 7227(A)
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Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (AMAN II) (MAN II) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) (Golgi alpha-mannosidase II) Q24451 (A)
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A
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1hty, 1hww, 1hxk, 1ps3, 1qwn, 1qwu, 1qx1, 2f7o, 2f7q, 2f7r
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| A |
alpha-mannosidase II |
Protein |
Q24451 (MAN2_DROME)
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1045 |
97% |
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| A |
SUGAR (N-ACETYL-D-GLUCOSAMINE) |
NAG
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| A |
ZINC ION |
ZN
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| A |
(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL |
2SK
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| A |
(4S)-2-METHYL-2,4-PENTANEDIOL |
MPD
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