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EBI PDBe PDBeView

PDBe Entry: 2f59 view

Lumazine synthase RibH1 from Brucella abortus (Gene BruAb1_0785, Swiss-Prot entry Q57DY1) complexed with inhibitor 5-Nitro-6-(D-Ribitylamino)-2,4(1H,3H) Pyrimidinedione
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.3 Å, R-factor: 21.7%, Free R-factor: 24.1%, Spacegroup: P 32 2 1
Released 28/11/2006, deposition: 25/11/2005, last revision: 24/02/2009
Authors Klinke, S.search; Zylberman, V.search; Bonomi, H.R.search; Haase, I.search; Guimaraes, B.G.search; Braden, B.C.search; Bacher, A.search; Fischer, M.search; Goldbaum, F.A.search
Primary citation Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales
J.MOL.BIOL.search vol:373, pag:664-680 (2007) [PubMed ID 17854827 ]search
Keywords Enzyme-substrate analoguesearch, inhibitor complexsearch, TRANSFERASEsearch
EC 2.5.1.9 ExPASy BRENDA search (A B C D E)
Organism Brucella abortus 235search(E A B C D)
UniProt 6,7-dimethyl-8-ribityllumazine synthase 1 (EC 2.5.1.9) (DMRL synthase 1) (Lumazine synthase 1) (Riboflavin synthase 1 beta chain) Q57DY1search (E A B C D)
Solvent A, B, C, D, E
Related entries 1di0, 1xn1, 1t13
Polymers
Id Name Type UniProt Residues Observed
E, A, B, C, D 6,7-dimethyl-8-ribityllumazine synthase 1 Protein Q57DY1 (RISB1_BRUAB)search
 157 93%
Heterogens
Id Name Ligands
A, B, C, D CALCIUM ION CA search
A, B, C, D, E 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE INI search
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