spacer Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680
Experimental details
Structure factors Download
Spacegroup P 1 21 1
Parameters
a:44.768Å b:59.417Å c:66.896Å
α:90.0° β:98.42° γ:90.0°
Refinement
Highest Resolution 1.91 Å
Lowest Resolution 44.29 Å
Number of reflections All:27297 Observed:23335 (85.5% complete) R-free:1612 (6.9%)
R-values All = 0.21 R = 0.21 Rwork = 0.21 Rfree = 0.24
Diffraction
Dataset 1
Temperature (K) Source Source type Wavelength (Å)
100.0 Synchrotron ALS BEAMLINE 8.2.1 1.0

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