2eyw Summary


N-terminal SH3 domain of CT10-Regulated Kinase

The structure was published by Kobashigawa, Y., Sakai, M., Naito, M., et al., Ogura, K., Tanaka, S., and Inagaki, F., in 2007 in a paper entitled "Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of v-crk sarcoma virus CT10 oncogene homolog isoform a. This molecule has the UniProt identifier P46108 (CRK_HUMAN)search. The sample contained 78 residues which is < 90% of the natural sequence. Out of 78 residues 77 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A v-crk sarcoma virus CT10 oncogene homolog isoform a P46108 (125-198) (CRK_HUMAN)search Homo sapienssearch 100% 78 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P46108 (125 - 198) v-crk sarcoma virus CT10 oncogene homolog isoform a Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P46108) SH3-domainsearch SH3 Domainssearch PF00018: SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch