2eyv Summary


SH2 domain of CT10-Regulated Kinase

The structure was published by Kobashigawa, Y., Sakai, M., Naito, M., et al., Ogura, K., Tanaka, S., and Inagaki, F., in 2007 in a paper entitled "Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of v-crk sarcoma virus CT10 oncogene homolog isoform a.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A v-crk sarcoma virus CT10 oncogene homolog isoform a P46108 (6-124) (CRK_HUMAN)search Homo sapienssearch 100% 124 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P46108 (6 - 124) v-crk sarcoma virus CT10 oncogene homolog isoform a Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P46108) SH2 domainsearch SHC Adaptor Proteinsearch PF00017: SH2 domainsearch
Chain InterPro annotation
A SH2 domainsearch