spacer The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide
CATH: Protein Structure Classification
CATH code 3.30.505.10 search
Name Tyrosine-protein kinase itk/tsk. Chain: a. Fragment: sh2 domain. Synonym: t-cell-specific kinase, il-2-inducible t-cell kinase, kinase emt,kinase tlk, itk. Engineered: yes. Lymphocyte cytosolic protein 2 phosphopeptide fragment. Chain: b. Fragment: phosphopeptide fragment, sequence database residues 143-148. Synonym: sh2 domain-containing leucocyte protein of 76 kda, slp-76 tyrosine phosphoprotein, slp76. Engineered: yes
Source Mus musculus. House mouse. Organism_taxid: 10090. Gene: itk, emt, tlk,tsk. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers A
Class Alpha Betasearch
Architecture 2-Layer Sandwich search
Topology SHC Adaptor Protein search
Homologous superfamily SHC Adaptor Protein search