2ef6 Summary


Canavalia gladiata lectin complexed with Man1-3Man-OMe

The structure was published by Bezerra, G.A., Oliveira, T.M., Moreno, F.B.M.B., et al., Delatorre, P., de Azevedo Jr., W.F., and Cavada, B.S., in 2007 in a paper entitled "Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: New insights into the understanding of the structure-biological activity relationship in legume lectins" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Concanavalin A.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Concanavalin A P14894 (28-148) (CONA_CANGL)search Canavalia gladiatasearch < 90% 237 98%
B Concanavalin A P14894 (28-148) (CONA_CANGL)search Canavalia gladiatasearch < 90% 237 98%
C Concanavalin A P14894 (28-148) (CONA_CANGL)search Canavalia gladiatasearch < 90% 237 98%
D Concanavalin A P14894 (28-148) (CONA_CANGL)search Canavalia gladiatasearch < 90% 237 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P14894 (28 - 148) Concanavalin A Canavalia gladiata

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C, D Jelly Rollssearch Legume lectin domainsearch

Chain ID Molecular function (GO)
A, B, C, D (P14894) carbohydrate bindingsearch

Chain InterPro annotation
A, B, C, D Legume lectin, alpha chain, conserved sitesearch Legume lectin domainsearch Concanavalin A-like lectin/glucanase domainsearch Legume lectin, beta chain, Mn/Ca-binding sitesearch