Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Epidermal growth factor receptor (preferred)
PDBe Complex ID:
PDB-CPX-132701 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 38.01 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Length: 334 amino acids
Theoretical weight: 38.01 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P00533 (Residues: 695-1022; Coverage: 28%)
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 22-ID
Spacegroup:
I23
Expression system: Spodoptera frugiperda
