2e9v Summary

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Structure of h-CHK1 complexed with A859017

A publication describing this structure is not available. The depositing authors are Park, C.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2007.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of Serine/threonine-protein kinase Chk1.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Serine/threonine-protein kinase Chk1 O14757 (2-269) (CHK1_HUMAN)search Homo sapienssearch < 90% 268 100%
B Serine/threonine-protein kinase Chk1 O14757 (2-269) (CHK1_HUMAN)search Homo sapienssearch < 90% 268 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O14757 (2 - 269) Serine/threonine-protein kinase Chk1 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Protein kinases, catalytic subunitsearch Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (O14757) ATP bindingsearch protein serine/threonine kinase activitysearch protein kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch protein phosphorylationsearch

Chain InterPro annotation
A, B Protein kinase domainsearch Serine/threonine- / dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch