Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo trimer (preferred)
Assembly name:
Soluble tumor necrosis factor complex (preferred)
PDBe Complex ID:
PDB-CPX-134285 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor, soluble form
Molecule details ›
Chains: A, B, C
Length: 157 amino acids
Theoretical weight: 17.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Length: 157 amino acids
Theoretical weight: 17.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P01375 (Residues: 77-233; Coverage: 67%)
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL41XU
Spacegroup:
P212121
Expression system: Escherichia coli BL21(DE3)
