2dzp Summary


Structure of mutant tryptophan synthase alpha-subunit (D17N) from a hyperthermophile, Pyrococcus furiosus

A publication describing this structure is not available. The depositing authors are Ogasahara, K.search; Yamagata, Y.search; Yutani, K.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search

This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2006.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of Tryptophan synthase alpha chain.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Tryptophan synthase alpha chain Q8U094 (1-248) (TRPA_PYRFU)search Pyrococcus furiosus DSM 3638search 100% 248 98%
B Tryptophan synthase alpha chain Q8U094 (1-248) (TRPA_PYRFU)search Pyrococcus furiosus DSM 3638search 100% 248 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8U094 (1 - 248) Tryptophan synthase alpha chain Pyrococcus furiosus

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q8U094) Aldolase class Isearch PF00290: Tryptophan synthase alpha chainsearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (Q8U094) tryptophan metabolic processsearch tryptophan biosynthetic processsearch cellular amino acid biosynthetic processsearch metabolic processsearch aromatic amino acid family biosynthetic processsearch catalytic activitysearch tryptophan synthase activitysearch lyase activitysearch

Chain InterPro annotation
A, B Tryptophan synthase, alpha chainsearch Ribulose-phosphate binding barrelsearch Aldolase-type TIM barrelsearch Tryptophan synthase, alpha chain, active sitesearch