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EBI PDBe PDBeView

PDBe Entry: 2dy4 view

Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol
Summary
Header TRANSFERASE/DNAsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.65 Å, R-factor: 22.9%, Free R-factor: 28.1%, Spacegroup: P 1 21 1
Released 09/01/2007, deposition: 06/09/2006, last revision: 12/01/2010
Authors Aller, P.search; Rould, M.A.search; Hogg, M.search; Wallace, S.S.search; Doublie, S.search
Primary citation A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol.
PROC.NATL.ACAD.SCI.USAsearch vol:104, pag:814-818 (2007) [PubMed ID 17210917 ]search
Keywords DNA polymerasesearch, DNA lesionsearch, thymine glycolsearch, oxidative thymine lesionsearch, TRANSFERASE/DNA COMPLEXsearch
EC 2.7.7.7 ExPASy BRENDA search (A B C D)
Organism Enterobacteria phage RB69 12353search(A B C D)
UniProt DNA polymerase (EC 2.7.7.7) (Gp43) Q38087search (A B C D)
Solvent A, B, C, D, E, F, G, H, I, J, K, L
Related entries 1clq, 1ig9, 1rv2, 1q9x, 1q9y, 2dtu
Polymers
Id Name Type UniProt Residues Observed
E, G, I, K 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3' DNA
18 100%
F, H, J, L 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3' DNA
15 100%
A, B, C, D DNA polymerase Protein Q38087 (DPOL_BPR69)search
 903 99%
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