2dnm

Solution NMR

Solution structure of RNA binding domain in SRp46 splicing factor

Released:
Source organism: Homo sapiens
Entry authors: Tsuda K, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-189689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/arginine-rich splicing factor 8 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q9BRL6 (Residues: 8-97; Coverage: 32%)
Gene names: SFRS2B, SRP46, SRSF8
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Cell free synthesis