› 2dn3

X-ray diffraction
1.25Å resolution

1.25A resolution crystal structure of human hemoglobin in the carbonmonoxy form

Released:
DOI: 10.2210/pdb2dn3/pdb
PDB entry 2dn3 coloured by chain, front view.
PDB entry 2dn3 coloured by chain, side view.
PDB entry 2dn3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
1.25 A resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms.
Park SY, Yokoyama T, Shibayama N, Shiro Y, Tame JR
J Mol Biol 360 690-701 (2006)
PMID: 16765986

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chain: B
Molecule details ›
Chain: B
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 2 x HEM
Ligand CMO 2 x CMO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44B2
Spacegroup: P41212
Unit cell:
a: 53.27Å b: 53.27Å c: 189.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 not available not available

Quick links

Citations

13 review citations

Heme on innate immunity and inflammation.
Dutra et al. (2014)
12 more

23 mentions without citation

New look at hemoglobin allostery.
Yuan et al. (2015)
22 more