› 2dkq

Solution NMR

Solution structure of the PTB domain of KIAA1075 protein from human

Released:
DOI: 10.2210/pdb2dkq/pdb
PDB entry 2dkq coloured by chain, ensemble of 20 models, front view.
PDB entry 2dkq coloured by chain, ensemble of 20 models, side view.
PDB entry 2dkq coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Li H, Tochio N, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179044 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tensin-2 Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 16.98 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q63HR2 (Residues: 1263-1409; Coverage: 10%)
Gene names: KIAA1075, TENC1, TNS2
Sequence domains: Phosphotyrosine-binding domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Cell free synthesis

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