› 2dj6

X-ray diffraction
2.1Å resolution

Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3

Released:
DOI: 10.2210/pdb2dj6/pdb
PDB entry 2dj6 coloured by chain, front view.
PDB entry 2dj6 coloured by chain, side view.
PDB entry 2dj6 coloured by chain, top view.
Source organism: Pyrococcus horikoshii OT3
Entry authors: Bagautdinov B, Kunishima N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
hypothetical protein PH0634 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 115 amino acids
Theoretical weight: 13.53 KDa
Source organism: Pyrococcus horikoshii OT3
Expression system: Escherichia coli
UniProt:
  • Canonical: O58368 (Residues: 1-115; Coverage: 100%)
Gene name: PH0634
Sequence domains: 6-pyruvoyl tetrahydropterin synthase
Structure domains: 6-pyruvoyl tetrahydropterin synthase/QueD

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P212121
Unit cell:
a: 35.831Å b: 95.708Å c: 105.654Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.2 0.23
Expression system: Escherichia coli

Quick links