2dhb Summary


PDB entry 2dhb (supersedes 1dhb)


The structure was published by Bolton, W. and Perutz, M.F., in 1970 in a paper entitled "Three dimensional fourier synthesis of horse deoxyhaemoglobin at 2.8 Angstrom units resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 1973.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely HEMOGLOBIN (DEOXY) (ALPHA CHAIN) and HEMOGLOBIN (DEOXY) (BETA CHAIN).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HEMOGLOBIN (DEOXY) (ALPHA CHAIN) P01958 (2-142) (HBA_HORSE)search Equus caballussearch 99% 141 100%
B HEMOGLOBIN (DEOXY) (BETA CHAIN) P02062 (1-146) (HBB_HORSE)search Equus caballussearch 100% 146 100%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P01958 (2 - 142) HEMOGLOBIN (DEOXY) (ALPHA CHAIN) Equus caballus
P02062 (1 - 146) HEMOGLOBIN (DEOXY) (BETA CHAIN) Equus caballus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P01958) Globinssearch Globinssearch PF00042: Globinsearch
B (P02062) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P01958) iron ion bindingsearch metal ion bindingsearch heme bindingsearch oxygen transporter activitysearch oxygen bindingsearch oxygen transportsearch transportsearch hemoglobin complexsearch
B (P02062) heme bindingsearch oxygen bindingsearch iron ion bindingsearch oxygen transporter activitysearch metal ion bindingsearch oxygen transportsearch transportsearch hemoglobin complexsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch