› 2dg6

X-ray diffraction
2.2Å resolution

Crystal structure of the putative transcriptional regulator SCO5550 from Streptomyces coelicolor A3(2)

Released:
DOI: 10.2210/pdb2dg6/pdb
PDB entry 2dg6 coloured by chain, front view.
PDB entry 2dg6 coloured by chain, side view.
PDB entry 2dg6 coloured by chain, top view.
Source organism: Streptomyces coelicolor A3(2)
Primary publication:
Structural and genomic DNA analysis of a putative transcription factor SCO5550 from Streptomyces coelicolor A3(2): regulating the expression of gene sco5551 as a transcriptional activator with a novel dimer shape.
Hayashi T, Tanaka Y, Sakai N, Watanabe N, Tamura T, Tanaka I, Yao M
Biochem Biophys Res Commun 435 28-33 (2013)
PMID: 23618855

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131476 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH merR-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.21 KDa
Source organism: Streptomyces coelicolor A3(2)
Expression system: Rhodococcus erythropolis
UniProt:
  • Canonical: O86531 (Residues: 1-214; Coverage: 100%)
Gene names: SC1C2.31c, SCO5550
Sequence domains: MerR family regulatory protein

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44B2
Spacegroup: P21212
Unit cell:
a: 49.689Å b: 100.442Å c: 38.989Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.276
Expression system: Rhodococcus erythropolis

Quick links

Citations

2 citation in other articles

Identification of Position-Specific Correlations between DNA-Binding Domains and Their Binding Sites. Application to the MerR Family of Transcription Factors.
Korostelev et al. (2016)
1 more