2dc5 Summary

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Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution

A publication describing this structure is not available. The depositing authors are Kamo, S.search; Kishishita, S.search; Murayama, K.search; Shirouzu, M.search; Yokoyama, S.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search

This crystal structure was determined using X-ray diffraction at a resolution of 1.6 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Glutathione S-transferase, mu 7.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Glutathione S-transferase, mu 7 Q80W21 (1-218) (GSTM7_MOUSE)search Mus musculussearch 100% 231 94%
B Glutathione S-transferase, mu 7 Q80W21 (1-218) (GSTM7_MOUSE)search Mus musculussearch 100% 231 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q80W21 (1 - 218) Glutathione S-transferase, mu 7 Mus musculus

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q80W21) Glutaredoxinsearch, Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2search PF00043: Glutathione S-transferase, C-terminal domainsearch, PF02798: Glutathione S-transferase, N-terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (Q80W21) glutathione transferase activitysearch glutathione bindingsearch transferase activitysearch receptor bindingsearch protein homodimerization activitysearch enzyme bindingsearch negative regulation of ryanodine-sensitive calcium-release channel activitysearch nitrobenzene metabolic processsearch positive regulation of ryanodine-sensitive calcium-release channel activitysearch xenobiotic catabolic processsearch cellular detoxification of nitrogen compoundsearch glutathione metabolic processsearch cellular response to caffeinesearch metabolic processsearch regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumsearch cytoplasmsearch sarcoplasmic reticulumsearch extracellular vesicular exosomesearch

Chain InterPro annotation
A, B Glutathione S-transferase, Mu classsearch Glutathione S-transferase, N-terminalsearch Glutathione S-transferase, C-terminalsearch Glutathione S-transferase, C-terminal-likesearch Thioredoxin-like foldsearch