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EBI PDBe PDBeView

PDBe Entry: 2cvz view

Structure of hydroxyisobutyrate dehydrogenase from thermus thermophilus HB8
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 18.16%, Free R-factor: 20.0%, Spacegroup: P 21 21 21
Released 28/06/2005, deposition: 14/06/2005, last revision: 24/02/2009
Authors Lokanath, N.K.search; Kunishima, N.search; Miyano, M.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search
Primary citation Crystal Structure of Novel NADP-dependent 3-Hydroxyisobutyrate Dehydrogenase from Thermus thermophilus HB8
J.MOL.BIOL.search vol:352, pag:905-917 (2005) [PubMed ID 16126223 ]search
Keywords hydroxyisobutyratesearch, valine catabolismsearch, NADP+search, structural genomicssearch, RIKEN Structural Genomics/Proteomics Initiativesearch, RSGIsearch, OXIDOREDUCTASEsearch
Organism Thermus thermophilus HB8 300852search(A B C D)
UniProt 3-hydroxyisobutyrate dehydrogenase Q5SLQ6search (A B C D)
Solvent A, B, C, D
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D 3-hydroxyisobutyrate dehydrogenase Protein Q5SLQ6 (Q5SLQ6_THET8)search
 289 100%
Heterogens
Id Name Ligands
B, A, C NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE NDP search
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