2ctn Summary



The structure was published by Sia, S.K., Li, M.X., Spyracopoulos, L., et al., Liu, W., Putkey, J.A., and Sykes, B.D., in 1997 in a paper entitled "Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1997.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of TROPONIN C. This molecule has the UniProt identifier P09860 (TNNC1_CHICK)search. The sample contained 89 residues which is < 90% of the natural sequence. Out of 89 residues 88 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TROPONIN C P09860 (3-89) (TNNC1_CHICK)search Gallus gallussearch 99% 89 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P09860 (3 - 89) TROPONIN C Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P09860) Calmodulin-likesearch EF-handsearch PF13833: EF-hand domain pairsearch

Chain ID Molecular function (GO)
A (P09860) calcium ion bindingsearch

Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch