STRUCTURAL INSIGHTS INTO THE DESIGN OF NONPEPTIDIC ISOTHIAZOLIDINONE-CONTAINING INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B
The structure was published by Ala, P.J., Gonneville, L., Hillman, M., et al., Burn, T.C., Hollis, G.F., and Wynn, R., in 2006 in a paper entitled "Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-Containing Inhibitors of Protein- Tyrosine Phosphatase 1B." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2006.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1. This molecule has the UniProt identifier P18031 (PTN1_HUMAN). The sample contained 321 residues which is < 90% of the natural sequence. Out of 321 residues 296 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: