2cmw Summary

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STRUCTURE OF HUMAN CASEIN KINASE 1 GAMMA-1 IN COMPLEX WITH 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE (CASP TARGET)

A publication describing this structure is not available. The depositing authors are Bunkoczi, G.search; Rellos, P.search; Das, S.search; Savitsky, P.search; Niesen, F.search; Sobott, F.search; Fedorov, O.search; Pike, A.C.W.search; Von Delft, F.search; Sundstrom, M.search; Arrowsmith, C.search; Edwards, A.search; Weigelt, J.search; Knapp, S.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.75 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of CASEIN KINASE I ISOFORM GAMMA-1.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CASEIN KINASE I ISOFORM GAMMA-1 Q9HCP0 (45-352) (KC1G1_HUMAN)search Homo sapienssearch < 90% 310 95%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9HCP0 (45 - 352) CASEIN KINASE I ISOFORM GAMMA-1 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch, Casein kinase 1 gamma C terminalsearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q9HCP0) ATP bindingsearch transferase activity, transferring phosphorus-containing groupssearch protein serine/threonine kinase activitysearch protein kinase activitysearch protein phosphorylationsearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch