2ckp Summary

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CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA-2 IN COMPLEX WITH ADP

The structure was published by Malito, E., Sekulic, N., Too, W.C., Konrad, M., and Lavie, A., in 2006 in a paper entitled "Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.1 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of CHOLINE KINASE ALPHA.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CHOLINE KINASE ALPHA P35790 (50-457) (CHKA_HUMAN)search Homo sapienssearch 100% 390 81%
B CHOLINE KINASE ALPHA P35790 (50-457) (CHKA_HUMAN)search Homo sapienssearch 100% 390 81%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P35790 (50 - 457) CHOLINE KINASE ALPHA Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (P35790) Choline kinase; domain 1search, Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2search PF01633: Choline/ethanolamine kinasesearch

Chain ID Molecular function (GO)
A, B (P35790) transferase activity, transferring phosphorus-containing groupssearch

Chain InterPro annotation
A, B Protein kinase-like domainsearch