2cke Summary

pdbe.org/2cke
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HUMAN DEATH-ASSOCIATED DRP-1 KINASE IN COMPLEX WITH INHIBITOR

A publication describing this structure is not available. The depositing authors are Kursula, P.search; Wilmanns, M.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of DEATH-ASSOCIATED PROTEIN KINASE 2.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A DEATH-ASSOCIATED PROTEIN KINASE 2 Q9UIK4 (11-330) (DAPK2_HUMAN)search Homo sapienssearch < 90% 321 93%
B DEATH-ASSOCIATED PROTEIN KINASE 2 Q9UIK4 (11-330) (DAPK2_HUMAN)search Homo sapienssearch < 90% 321 93%
C DEATH-ASSOCIATED PROTEIN KINASE 2 Q9UIK4 (11-330) (DAPK2_HUMAN)search Homo sapienssearch < 90% 321 93%
D DEATH-ASSOCIATED PROTEIN KINASE 2 Q9UIK4 (11-330) (DAPK2_HUMAN)search Homo sapienssearch < 90% 321 93%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9UIK4 (11 - 330) DEATH-ASSOCIATED PROTEIN KINASE 2 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C, D Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B, C, D (Q9UIK4) ATP bindingsearch protein serine/threonine kinase activitysearch protein kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch protein phosphorylationsearch

Chain InterPro annotation
A, B, C, D Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch Myosin light chain kinase-relatedsearch