2cjw Summary

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CRYSTAL STRUCTURE OF THE SMALL GTPASE GEM (GEMDNDCAM) IN COMPLEX TO MG.GDP

The structure was published by Splingard, A., Menetrey, J., Perderiset, M., et al., Wells, A., Houdusse, A., and De Gunzburg, J., in 2007 in a paper entitled "Biochemical and Structural Characterization of the Gem Gtpase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely GTP-BINDING PROTEIN GEM.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A GTP-BINDING PROTEIN GEM P55040 (74-261) (GEM_HUMAN)search Homo sapienssearch < 90% 192 92%
B GTP-BINDING PROTEIN GEM P55040 (74-261) (GEM_HUMAN)search Homo sapienssearch < 90% 192 90%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P55040 (74 - 261) GTP-BINDING PROTEIN GEM Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A P-loop containing nucleotide triphosphate hydrolasessearch Ras familysearch
B P-loop containing nucleotide triphosphate hydrolasessearch Ras familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P55040) GTP catabolic processsearch signal transductionsearch small GTPase mediated signal transductionsearch GTP bindingsearch membranesearch
B (P55040) small GTPase mediated signal transductionsearch GTP catabolic processsearch signal transductionsearch GTP bindingsearch membranesearch

Chain InterPro annotation
A Small GTPase superfamilysearch Small GTP-binding protein domainsearch Small GTPase superfamily, Ras typesearch P-loop containing nucleoside triphosphate hydrolasesearch
B Small GTPase superfamilysearch Small GTP-binding protein domainsearch Small GTPase superfamily, Ras typesearch P-loop containing nucleoside triphosphate hydrolasesearch