A PHARMACOLOGICAL MAP OF THE PI3-K FAMILY DEFINES A ROLE FOR P110ALPHA IN SIGNALING: THE STRUCTURE OF COMPLEX OF PHOSPHOINOSITIDE 3-KINASE GAMMA WITH INHIBITOR PIK-90
The structure was published by Knight, Z.A., Gonzalez, B., Feldman, M.E., et al., Weiss, W.A., Williams, R.L., and Shokat, K.M., in 2006 in a paper entitled "A Pharmacological Map of the Pi3-K Family Defines a Role for P110Alpha in Signaling" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: