2cfv Summary

pdbe.org/2cfv
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Crystal structure of human protein tyrosine phosphatase receptor type J

The structure was published by Barr, A.J., Ugochukwu, E., Lee, W.H., et al., Burgess-Brown, N.A., Muller, S., and Knapp, S., in 2009 in a paper entitled "Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of HUMAN PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE J.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HUMAN PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE J Q12913 (1019-1311) (PTPRJ_HUMAN)search Homo sapienssearch < 90% 316 84%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q12913 (1019 - 1311) HUMAN PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE J Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Protein tyrosine phosphatase superfamilysearch Protein-tyrosine phosphatasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q12913) phosphatase activitysearch protein tyrosine phosphatase activitysearch dephosphorylationsearch protein dephosphorylationsearch

Chain InterPro annotation
A Protein-tyrosine phosphatase, receptor/non-receptor typesearch Protein-tyrosine/Dual specificity phosphatasesearch Protein-tyrosine phosphatase, active sitesearch Protein-tyrosine phosphatase-likesearch