spacer STRUCTURE OF TRYPANOSOMA BRUCEI PTERIDINE REDUCTASE (PTR1) IN TERNARY COMPLEX WITH COFACTOR AND THE ANTIFOLATE METHOTREXATE
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: PTERIDINE REDUCTASE

1 M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V X Q
M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V C Q
1
61 A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
121 A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P X M A F S L Y N M G K H A
A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P C M A F S L Y N M G K H A
181 L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
241 V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
268

Regions

UniProt

O76290
1 .. 268 > 1 .. 268 (PDB)

Pfam

PF13561
10 .. 264 (PDB)

Chain B: PTERIDINE REDUCTASE

1 M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V X Q
M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V C Q
1
61 A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
121 A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P X M A F S L Y N M G K H A
A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P C M A F S L Y N M G K H A
181 L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
241 V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
268

Regions

UniProt

O76290
1 .. 268 > 1 .. 268 (PDB)

Pfam

PF13561
10 .. 264 (PDB)

Chain C: PTERIDINE REDUCTASE

1 M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V X Q
M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V C Q
1
61 A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
121 A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P X M A F S L Y N M G K H A
A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P C M A F S L Y N M G K H A
181 L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
241 V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
268

Regions

UniProt

O76290
1 .. 268 > 1 .. 268 (PDB)

Pfam

PF13561
10 .. 264 (PDB)

Chain D: PTERIDINE REDUCTASE

1 M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V X Q
M E A P A A V V T G A A K R I G R A I A V K L H Q T G Y R V V I H Y H N S A E A A V S L A D E L N K E R S N T A V V C Q
1
61 A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
A D L T N S N V L P A S C E E I I N S C F R A F G R C D V L V N N A S A F Y P T P L V Q G D H E D N S N G K T V E T Q V
121 A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P X M A F S L Y N M G K H A
A E L I G T N A I A P F L L T M S F A Q R Q K G T N P N C T S S N L S I V N L C D A M V D Q P C M A F S L Y N M G K H A
181 L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
L V G L T Q S A A L E L A P Y G I R V N G V A P G V S L L P V A M G E E E K D K W R R K V P L G R R E A S A E Q I A D A
241 V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
V I F L V S G S A Q Y I T G S I I K V D G G L S L V H A
268

Regions

UniProt

O76290
1 .. 268 > 1 .. 268 (PDB)

Pfam

PF13561
10 .. 264 (PDB)
spacer