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PDBe Entry: 2c6p 
MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN COMPLEX WITH PHOSPHATE ANION
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 2.39 Å, R-factor: 20.0%, Free R-factor: 25.1%, Spacegroup: I 2 2 2
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15/02/2006, deposition: 11/11/2005, last revision: 24/02/2009
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Mesters, J.R.; Barinka, C.; Li, W.; Tsukamoto, T.; Majer, P.; Slusher, B.S.; Konvalinka, J.; Hilgenfeld, R.
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Structure of Glutamate Carboxypeptidase II, a Drug Target in Neuronal Damage and Prostate Cancer.
EMBO J. vol:25, pag:1375 (2006) [PubMed ID 16467855 ]
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NAALADASE, NEURODEGENERATIVE DISEASE, PEPTIDASE, PROSTATE CANCER, PSMA, GLYCOPROTEIN, HYDROLASE, ALTERNATIVE SPLICING, ANTIGEN, CARBOXYPEPTIDASE, DIPEPTIDASE, METAL-BINDING, METALLOPROTEASE, MULTIFUNCTIONAL ENZYME, POLYMORPHISM, SIGNAL-ANCHOR, TRANSMEMBRANE, ZINC
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3.4.17.21 ExPASy BRENDA (A)
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Homo sapiens(human) 9606(A)
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Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate-specific membrane antigen) (PSMA) (PSM) Q04609 (A)
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A
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1z8l, 2c6c, 2c6g
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| A |
GLUTAMATE CARBOXYPEPTIDASE II |
Protein |
Q04609 (FOLH1_HUMAN)
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707 |
95% |
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| A |
ZINC ION |
ZN
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| A |
CALCIUM ION |
CA
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| A |
CHLORIDE ION |
CL
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| A |
SUGAR (2-MER) |
NAG
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| A |
SUGAR (N-ACETYL-D-GLUCOSAMINE) |
NAG
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| A |
SUGAR (3-MER) |
NAG
BMA
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| A |
PHOSPHATE ION |
PO4
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