PDB entry 2c5v (supersedes 1oku)
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
The structure was published by Kontopidis, G., Mcinnes, C., Pandalaneni, S.R., et al., Wang, S., Walkinshaw, M.D., and Fischer, P.M., in 2006 in a paper entitled "Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2005.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, and ALA-ALA-ABA-ARG-SER-LEU-ILE-PFF-NH2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: