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EBI PDBe PDBeView

PDBe Entry: 2c3u view

CRYSTAL STRUCTURE OF PYRUVATE-FERREDOXIN OXIDOREDUCTASE FROM DESULFOVIBRIO AFRICANUS, OXYGEN INHIBITED FORM
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.32 Å, R-factor: 18.7%, Free R-factor: 23.8%, Spacegroup: P 21 21 21
Released 15/02/2006, deposition: 12/10/2005, last revision: 24/02/2009
Authors Cavazza, C.search; Contreras-Martel, C.search; Pieulle, L.search; Chabriere, E.search; Hatchikian, E.C.search; Fontecilla-Camps, J.C.search
Primary citation Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate.
STRUCTUREsearch vol:14, pag:217 (2006) [PubMed ID 16472741 ]search
Keywords OXIDOREDUCTASEsearch, 4FE-4Ssearch, IRONsearch, IRON-SULFURsearch, IRON-SULFUR CLUSTERsearch, PYRUVATE CATABOLISMsearch, TPP-DEPENDENT ENZYMEsearch, METAL-BINDINGsearch, ELECTRON TRANSPORTsearch
Organism Desulfovibrio africanus 873search(A B)
UniProt Pyruvate-ferredoxin oxidoreductase P94692search (A B)
Solvent A, B
Related entries 1b0p, 1kek, 2pda, 2c3m, 2c3o, 2c3p, 2c3y, 2c42
Polymers
Id Name Type UniProt Residues Observed
A, B PYRUVATE-FERREDOXIN OXIDOREDUCTASE Protein P94692 (P94692_DESAF)search
 1231 100%
Heterogens
Id Name Ligands
A, B IRON/SULFUR CLUSTER SF4 search
A, B 2-(3-{[4-(HYDROXYAMINO)-2-METHYLPYRIMIDIN-5-YL]METHYL}-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL)ETHYL TRIHYDROGEN DIPHOSPHATE 2TP search
A, B PYRUVIC ACID PYR search
A, B MAGNESIUM ION MG search
A, B CALCIUM ION CA search
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