2bzh Summary

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CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1

A publication describing this structure is not available. The depositing authors are Debreczeni, J.E.search; Bullock, A.search; Knapp, S.search; Von Delft, F.search; Sundstrom, M.search; Arrowsmith, C.search; Weigelt, J.search; Edwards, A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1. This molecule has the UniProt identifier P11309 (PIM1_HUMAN)search. The sample contained 313 residues which is < 90% of the natural sequence. Out of 313 residues 271 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
B PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1 P11309 (92-404) (PIM1_HUMAN)search Homo sapienssearch < 90% 313 87%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P11309 (92 - 404) PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
B Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Biological process (GO) Molecular function (GO)
B (P11309) protein phosphorylationsearch protein kinase activitysearch protein serine/threonine kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch ATP bindingsearch

Chain InterPro annotation
B Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch