2byr Summary

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CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA IN COMPLEX WITH METHYLLYCACONITINE

The structure was published by Hansen, S.B., Sulzenbacher, G., Huxford, T., Marchot, P., Taylor, P., and Bourne, Y., in 2005 in a paper entitled "Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.45 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of ACETYLCHOLINE-BINDING PROTEIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
B ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
C ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
D ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
E ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
F ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
G ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
H ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
I ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%
J ACETYLCHOLINE-BINDING PROTEIN Q8WSF8 (18-236) (Q8WSF8_APLCA)search Aplysia californicasearch 90% 227 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8WSF8 (18 - 236) ACETYLCHOLINE-BINDING PROTEIN Aplysia californica

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F, G, H, I, J (Q8WSF8) Acetylcholine Binding Protein; Chain: A,search PF02931: Neurotransmitter-gated ion-channel ligand binding domainsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A, B, C, D, E, F, G, H, I, J (Q8WSF8) transportsearch ion transportsearch ion transmembrane transportsearch membranesearch integral component of membranesearch metal ion bindingsearch extracellular ligand-gated ion channel activitysearch

Chain InterPro annotation
A, B, C, D, E, F, G, H, I, J Neurotransmitter-gated ion-channelsearch Neurotransmitter-gated ion-channel ligand-binding domainsearch