DESIGN AND DISCOVERY OF NOVEL, POTENT THROMBIN INHIBITORS WITH A SOLUBILIZING CATIONIC P1-P2-LINKER
The structure was published by Bulat, S., Bosio, S., Papadopoulos, M.A., et al., Schamberger, J., Sekul, R., and Feurer, A., in 2006 in a paper entitled "Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2005.
The experimental data on which the structure is based was not deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely ALPHA THROMBIN and HIRUDIN.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: