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PDBe Entry: 2bu8 
CRYSTAL STRUCTURES OF HUMAN PYRUVATE DEHYDROGENASE KINASE 2 CONTAINING PHYSIOLOGICAL AND SYNTHETIC LIGANDS
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TRANSFERASE
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X-RAY DIFFRACTION
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Resolution: 2.5 Å, R-factor: 23.3%, Free R-factor: 24.05%, Spacegroup: P 64
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02/02/2006, deposition: 08/06/2005, last revision: 24/02/2009
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Knoechel, T.R.; Tucker, A.D.; Robinson, C.M.; Phillips, C.; Taylor, W.; Bungay, P.J.; Kasten, S.A.; Roche, T.E.; Brown, D.G.
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Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands.
BIOCHEMISTRY vol:45, pag:402 (2006) [PubMed ID 16401071 ]
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TRANSFERASE, PYRUVATE DEHYDROGENASE KINASE 2 GHKL MOTIF REGULATION
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2.7.11.2 ExPASy BRENDA (A)
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Homo sapiens(human) 9606(A)
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[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) Q15119 (A)
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A
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2btz, 2bu2, 2bu5, 2bu6, 2bu7
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| A |
PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2 |
Protein |
Q15119 (PDK2_HUMAN)
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394 |
91% |
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| A |
ADENOSINE-5'-DIPHOSPHATE |
ADP
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| A |
MAGNESIUM ION |
MG
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| A |
DICHLORO-ACETIC ACID |
TF4
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