2bdo Summary

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SOLUTION STRUCTURE OF HOLO-BIOTINYL DOMAIN FROM ACETYL COENZYME A CARBOXYLASE OF ESCHERICHIA COLI DETERMINED BY TRIPLE-RESONANCE NMR SPECTROSCOPY

The structure was published by Roberts, E.L., Shu, N., Howard, M.J., et al., Morris, T., Cronan Jr., J.E., and Perham, R.N., in 1999 in a paper entitled "Solution structures of apo and holo biotinyl domains from acetyl coenzyme A carboxylase of Escherichia coli determined by triple-resonance nuclear magnetic resonance spectroscopy." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PROTEIN (ACETYL-COA CARBOXYLASE). This molecule has the UniProt identifier P0ABD8 (BCCP_ECOLI)search. The sample contained 80 residues which is < 90% of the natural sequence. Out of 80 residues 80 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (ACETYL-COA CARBOXYLASE) P0ABD8 (77-156) (BCCP_ECOLI)search Escherichia coli K-12search 100% 80 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0ABD8 (77 - 156) PROTEIN (ACETYL-COA CARBOXYLASE) Escherichia coli BL21(DE3)

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P0ABD8) Biotinyl/lipoyl-carrier proteins and domainssearch OB fold (Dihydrolipoamide Acetyltransferase, E2P)search PF00364: Biotin-requiring enzymesearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P0ABD8) fatty acid biosynthetic processsearch acetyl-CoA carboxylase activitysearch acetyl-CoA carboxylase complexsearch

Chain InterPro annotation
A Biotin/lipoyl attachmentsearch Acetyl-CoA biotin carboxyl carriersearch Biotin-binding sitesearch Single hybrid motifsearch