› 2bde

X-ray diffraction
2.9Å resolution

Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1

Released:
DOI: 10.2210/pdb2bde/pdb
PDB entry 2bde coloured by chain, front view.
PDB entry 2bde coloured by chain, side view.
PDB entry 2bde coloured by chain, top view.
Source organism: Legionella pneumophila
Entry authors: Forouhar F, Abashidze M, Ho CK, Conover K, Acton TB, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178739 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytosolic IMP-GMP specific 5'-nucleotidase Chain: A
Molecule details ›
Chain: A
Length: 470 amino acids
Theoretical weight: 55.16 KDa
Source organism: Legionella pneumophila
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5ZZB6 (Residues: 1-459; Coverage: 100%)
Gene name: lpg0095
Sequence domains: 5' nucleotidase family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: I4122
Unit cell:
a: 152.54Å b: 152.54Å c: 188.406Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.221 0.267
Expression system: Escherichia coli

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