2bbn Summary

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SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR

The structure was published by Ikura, M., Clore, G.M., Gronenborn, A.M., Zhu, G., Klee, C.B., and Bax, A., in 1992 in a paper entitled "Solution structure of a calmodulin-target peptide complex by multidimensional NMR." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1992.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely CALMODULIN and MYOSIN LIGHT CHAIN KINASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CALMODULIN P62152 (2-149) (CALM_DROME)search Drosophila melanogastersearch 99% 148 100%
B MYOSIN LIGHT CHAIN KINASE P07313 (578-603) (MYLK2_RABIT)search Oryctolagus cuniculussearch < 90% 26 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P62152 (2 - 149) CALMODULIN Drosophila melanogaster
P07313 (578 - 603) MYOSIN LIGHT CHAIN KINASE

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P62152) Calmodulin-likesearch EF-handsearch PF13499: EF-hand domain pairsearch, PF13833: EF-hand domain pairsearch
B

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (P62152) microtubule associated complexsearch centriolesearch spindle polesearch cytoplasmsearch rhabdomeresearch myosin V complexsearch spindlesearch midbodysearch myosin VI complexsearch myosin VI head/neck bindingsearch myosin V bindingsearch calcium ion bindingsearch protein bindingsearch calmodulin bindingsearch metal ion bindingsearch myosin heavy chain bindingsearch regulation of response to DNA damage stimulussearch deactivation of rhodopsin mediated signalingsearch photoreceptor cell axon guidancesearch actin filament-based movementsearch spindle assembly involved in mitosissearch mitotic spindle organizationsearch sensory perception of soundsearch positive regulation of NFAT protein import into nucleussearch adaptation of rhodopsin mediated signalingsearch regulation of light-activated channel activitysearch kinetochore organizationsearch lateral inhibitionsearch centriole replicationsearch rhodopsin mediated signaling pathwaysearch metarhodopsin inactivationsearch protein phosphorylationsearch rhabdomere developmentsearch muscle cell cellular homeostasissearch

Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch
B