2bbm Summary

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SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR

The structure was published by Ikura, M., Clore, G.M., Gronenborn, A.M., Zhu, G., Klee, C.B., and Bax, A., in 1992 in a paper entitled "Solution structure of a calmodulin-target peptide complex by multidimensional NMR." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1992.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely CALMODULIN and MYOSIN LIGHT CHAIN KINASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CALMODULIN P62152 (2-149) (CALM_DROME)search Drosophila melanogastersearch 99% 148 100%
B MYOSIN LIGHT CHAIN KINASE P07313 (578-603) (MYLK2_RABIT)search Oryctolagus cuniculussearch < 90% 26 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P62152 (2 - 149) CALMODULIN Drosophila melanogaster
P07313 (578 - 603) MYOSIN LIGHT CHAIN KINASE

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P62152) Calmodulin-likesearch EF-handsearch PF13499: EF-hand domain pairsearch, PF13833: EF-hand domain pairsearch
B

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P62152) mitotic spindle organizationsearch metarhodopsin inactivationsearch spindle assembly involved in mitosissearch lateral inhibitionsearch photoreceptor cell axon guidancesearch regulation of response to DNA damage stimulussearch centriole replicationsearch protein phosphorylationsearch sensory perception of soundsearch regulation of light-activated channel activitysearch kinetochore organizationsearch muscle cell cellular homeostasissearch adaptation of rhodopsin mediated signalingsearch rhodopsin mediated signaling pathwaysearch rhabdomere developmentsearch deactivation of rhodopsin mediated signalingsearch actin filament-based movementsearch positive regulation of NFAT protein import into nucleussearch spindle polesearch microtubule associated complexsearch rhabdomeresearch myosin V complexsearch spindlesearch myosin VI complexsearch midbodysearch centriolesearch cytoplasmsearch calcium ion bindingsearch myosin VI head/neck bindingsearch protein bindingsearch metal ion bindingsearch myosin V bindingsearch myosin heavy chain bindingsearch calmodulin bindingsearch

Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch
B