p38alpha MAP kinase bound to MPAQ
The structure was published by Sullivan, J.E., Holdgate, G.A., Campbell, D., et al., Read, J., Vanscyoc, W.S., and Ward, W.H., in 2005 in a paper entitled "Prevention of MKK6-Dependent Activation by Binding to p38alpha MAP Kinase" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2005.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Mitogen-activated protein kinase 14. This molecule has the UniProt identifier Q16539 (MK14_HUMAN). The sample contained 365 residues which is 100% of the natural sequence. Out of 365 residues 334 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: