› 2b9e

X-ray diffraction
1.65Å resolution

Human NSUN5 protein

Released:
DOI: 10.2210/pdb2b9e/pdb
PDB entry 2b9e coloured by chain, front view.
PDB entry 2b9e coloured by chain, side view.
PDB entry 2b9e coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Min JR, Wu H, Zeng H, Loppnau P, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Plotnikov AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188656 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
28S rRNA (cytosine-C(5))-methyltransferase Chain: A
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 33.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96P11 (Residues: 127-429; Coverage: 71%)
Gene names: NSUN5, NSUN5A, WBSCR20, WBSCR20A
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SAM 1 x SAM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P3121
Unit cell:
a: 56.289Å b: 56.289Å c: 178.666Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.222
Expression system: Escherichia coli

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