2b86 Summary


Solution structure of the first Src homology 3 domain of Nck2

The structure was published by Park, S., Takeuchi, K., and Wagner, G., in 2006 in a paper entitled "Solution structure of the first SRC homology 3 domain of human nck2" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Cytoplasmic protein NCK2. This molecule has the UniProt identifier O43639 (NCK2_HUMAN)search. The sample contained 67 residues which is < 90% of the natural sequence. Out of 67 residues 59 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Cytoplasmic protein NCK2 O43639 (1-59) (NCK2_HUMAN)search Homo sapienssearch < 90% 67 88%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O43639 (1 - 59) Cytoplasmic protein NCK2 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH3 domainsearch

Chain ID Molecular function (GO)
A (O43639) protein kinase regulator activitysearch

Chain InterPro annotation
A SH3 domainsearch Cytoplasmic protein NCK2search