spacer
EBI PDBe PDBeView

PDBe Entry: 2b7o view

The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.3 Å, R-factor: 18.966%, Free R-factor: 22.429%, Spacegroup: P 32 2 1
Released 18/10/2005, deposition: 05/10/2005, last revision: 06/05/2008
Authors Webby, C.J.search; Baker, H.M.search; Lott, J.S.search; Baker, E.N.search; Parker, E.J.search; Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)search
Primary citation The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes
J.MOL.BIOL.search vol:354, pag:927-939 (2005) [PubMed ID 16288916 ]search
Keywords Mycobacterium tuberculosissearch, DAH7PS synthasesearch, Shikimate pathwaysearch, aromatic biosynthesissearch, evolutionary relationshipssearch, Structural Genomicssearch, Mycobacterium Tuberculosis Structural Proteomics Projectsearch, XMTBsearch, TRANSFERASEsearch
EC 2.5.1.54 ExPASy BRENDA search (A B)
Organism Mycobacterium tuberculosis H37Rv 83332search(A B)
UniProt Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible) (EC 2.5.1.54) O53512search (A B)
Solvent A, B
Polymers
Id Name Type UniProt Residues Observed
A, B 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG Protein O53512 (O53512_MYCTU)search
 464 97%
Heterogens
Id Name Ligands
A, B MANGANESE (II) ION MN search
A, B SULFATE ION SO4 search
A, B PHOSPHOENOLPYRUVATE PEP search
A O-DODECANYL OCTAETHYLENE GLYCOL CE1 search
spacer