Function and Biology Details
Reaction catalysed:
S-adenosyl 3-(methylthio)propylamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Spermidine/spermine synthases
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- Polyamine biosynthesis domain, conserved site
- Spermidine synthase, tetramerisation domain
- Polyamine biosynthesis domain
- Spermidine synthase, tetramerisation domain superfamily
- Spermidine/spermine synthase, eukaryotes
Structure domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PABS domain-containing protein (preferred)
PDBe Complex ID:
PDB-CPX-124517 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PABS domain-containing protein
Molecule details ›
Chains: A, B
Length: 314 amino acids
Theoretical weight: 35.07 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 314 amino acids
Theoretical weight: 35.07 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
- Canonical:
G5EFG3 (Residues: 1-314; Coverage: 100%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
P21
Expression system: Escherichia coli
