spacer Crystal Structure of TNF-alpha with a small molecule inhibitor
CATH: Protein Structure Classification
CATH code search
2az5A00 , 2az5B00 , 2az5C00 , 2az5D00
Name Tumor necrosis factor (tnf-alpha) (tumor necrosis factor ligand superfamily member 2) (tnf-a) (cachectin) [contains: tumor necrosis factor,membrane form. Tumor necrosis factor, soluble form]. Chain: a, b, c, d. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: tnf, tnfa, tnfsf2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers A, B, C, D
Class Mainly Betasearch
Architecture Sandwich search
Topology Jelly Rolls search
Homologous superfamily Jelly Rolls search