Assemblies
Multimeric state:
hetero trimer
Accessible surface area:
24876.76 Å2
Buried surface area:
5959.75 Å2
Dissociation area:
1,493.5
Å2
Dissociation energy (ΔGdiss):
18.55
kcal/mol
Dissociation entropy (TΔSdiss):
12.74
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-158185
Multimeric state:
hetero hexamer
Accessible surface area:
48640.59 Å2
Buried surface area:
13052.34 Å2
Dissociation area:
564.37
Å2
Dissociation energy (ΔGdiss):
1.98
kcal/mol
Dissociation entropy (TΔSdiss):
14.74
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-158187
Multimeric state:
hetero hexamer
Accessible surface area:
50239.93 Å2
Buried surface area:
11454.83 Å2
Dissociation area:
564.37
Å2
Dissociation energy (ΔGdiss):
1.95
kcal/mol
Dissociation entropy (TΔSdiss):
14.76
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-158187
Macromolecules
Chain: A
Length: 159 amino acids
Theoretical weight: 18.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 159 amino acids
Theoretical weight: 18.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P63208 (Residues: 2-160; Coverage: 98%)
Pfam:
InterPro:
- SKP1/BTB/POZ domain superfamily
- S-phase kinase-associated protein 1
- S-phase kinase-associated protein 1-like
- SKP1 component, POZ domain
- SKP1-like, dimerisation domain superfamily
- SKP1 component, dimerisation
Chain: B
Length: 336 amino acids
Theoretical weight: 37.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: F-box-like
InterPro:
SCOP:
Length: 336 amino acids
Theoretical weight: 37.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q13309 (Residues: 89-424; Coverage: 79%)
Pfam: F-box-like
InterPro:
- Leucine-rich repeat domain superfamily
- F-box-like domain superfamily
- F-box domain
- Leucine-rich repeat, cysteine-containing subtype
SCOP:
Chain: C
Length: 69 amino acids
Theoretical weight: 8.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Cyclin-dependent kinase regulatory subunit
InterPro:
CATH: Cyclin-dependent kinase, regulatory subunit
SCOP: Cell cycle regulatory proteins
Length: 69 amino acids
Theoretical weight: 8.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P61024 (Residues: 5-73; Coverage: 87%)
Pfam: Cyclin-dependent kinase regulatory subunit
InterPro:
CATH: Cyclin-dependent kinase, regulatory subunit
SCOP: Cell cycle regulatory proteins