Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + N(tau)-methylhistamine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Histamine N-methyltransferase (preferred)
PDBe Complex ID:
PDB-CPX-156132 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histamine N-methyltransferase
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 33.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
Length: 292 amino acids
Theoretical weight: 33.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P50135 (Residues: 1-292; Coverage: 100%)
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
Histamine N-methyltransferase
Molecule details ›
Chain: B
Length: 292 amino acids
Theoretical weight: 33.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
Length: 292 amino acids
Theoretical weight: 33.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P50135 (Residues: 1-292; Coverage: 100%)
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
