orally active thrombin inhibitors in complex with thrombin and an exosite decapeptide
The structure was published by Lange, U.E.W., Baucke, D., Hornberger, W., Mack, H., Seitz, W., and Hoeffken, H.W., in 2006 in a paper entitled "Orally active thrombin inhibitors. Part 2: optimization of the P2-moiety" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.46 Å and deposited in 2005.
The experimental data on which the structure is based was not deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Thrombin heavy chain, Thrombin light chain, and synthetic peptide.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: